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Andrew Whelton Selected Research

Febuxostat

1/2022Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial.
1/2019Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
3/2018Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.
1/2018Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study.
1/2018The influence of febuxostat on coronary artery endothelial dysfunction in patients with coronary artery disease: A phase 4 randomized, placebo-controlled, double-blind, crossover trial.
11/2017Effect of Febuxostat on Ambulatory Blood Pressure in Subjects With Hyperuricemia and Hypertension: A Phase 2 Randomized Placebo-Controlled Study.
1/2016Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment.
1/2013Preservation of renal function during gout treatment with febuxostat: a quantitative study.
1/2011Renal function in gout: long-term treatment effects of febuxostat.

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Andrew Whelton Research Topics

Disease

10Hypertension (High Blood Pressure)
11/2017 - 02/2002
7Gout
01/2022 - 01/2011
7Osteoarthritis
11/2011 - 04/2002
6Edema (Dropsy)
11/2011 - 02/2002
5Arthritis (Polyarthritis)
01/2007 - 02/2002
4Heart Failure
05/2006 - 02/2002
2Cardiovascular Diseases (Cardiovascular Disease)
03/2018 - 05/2006
2Hyperuricemia
01/2018 - 11/2017
2Pain (Aches)
11/2011 - 05/2006
2Heart Diseases (Heart Disease)
05/2006 - 10/2002
2Myocardial Infarction
09/2002 - 02/2002
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2018
1Chronic Kidney Failure (Chronic Renal Failure)
01/2018
1Thrombosis (Thrombus)
04/2010
1Thrombocytopenia (Thrombopenia)
04/2010
1Pulmonary Embolism
04/2010
1Venous Thrombosis (Deep-Vein Thrombosis)
04/2010
1Acute Kidney Injury (Acute Renal Failure)
05/2006
1Nephrotic Syndrome (Syndrome, Nephrotic)
05/2006
1Acidosis
05/2006
1Type 2 Diabetes Mellitus (MODY)
01/2005
1Rheumatoid Arthritis
07/2004
1Weight Gain
11/2002
1Myocardial Ischemia (Ischemic Heart Diseases)
10/2002
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
10/2002
1Body Weight (Weight, Body)
04/2002
1Essential Hypertension
04/2002
1Stroke (Strokes)
02/2002

Drug/Important Bio-Agent (IBA)

9FebuxostatFDA Link
01/2022 - 01/2011
9Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
05/2006 - 02/2002
9Celecoxib (Celebrex)FDA Link
05/2006 - 02/2002
7rofecoxib (Vioxx)FDA Link
05/2006 - 06/2002
6Uric Acid (Urate)IBA
01/2022 - 01/2011
4Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2006 - 04/2002
4Naproxen (Naprosyn)FDA LinkGeneric
01/2005 - 10/2002
3Xanthine OxidaseIBA
03/2018 - 11/2017
3Pharmaceutical PreparationsIBA
01/2018 - 06/2002
3DiureticsIBA
11/2011 - 06/2002
3Antihypertensive Agents (Antihypertensives)IBA
11/2011 - 04/2002
3Ibuprofen (Motrin)FDA LinkGeneric
07/2004 - 10/2002
3Diclofenac (SR 38)FDA LinkGeneric
07/2004 - 10/2002
2Allopurinol (Remid)FDA LinkGeneric
01/2022 - 03/2018
2Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
05/2006 - 01/2005
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
11/2002 - 04/2002
1purineIBA
03/2018
1lanthanum carbonate (Fosrenol)FDA Link
01/2018
1AntithrombinsIBA
04/2010
1Heparin (Liquaemin)FDA LinkGeneric
04/2010
1desirudin (Iprivask)FDA Link
04/2010
1argatroban (MPQA)FDA Link
04/2010
1Cyclooxygenase InhibitorsIBA
01/2007
1Acetaminophen (Paracetamol)FDA LinkGeneric
05/2006
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
05/2006
1ElectrolytesIBA
05/2006
1ProstaglandinsIBA
05/2006
1Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA
05/2006
1AcidsIBA
05/2006
1Acetazolamide (Diamox)FDA LinkGeneric
05/2006
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
05/2006
1Bicarbonates (Hydrogen Carbonate)IBA
05/2006
1valdecoxib (Bextra)FDA Link
07/2004
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
11/2002
1Lisinopril (Prinivil)FDA LinkGeneric
04/2002
1CreatinineIBA
04/2002
1PotassiumIBA
04/2002

Therapy/Procedure

7Therapeutics
01/2013 - 06/2002
1Aftercare (After-Treatment)
01/2022
1Drug Therapy (Chemotherapy)
11/2011
1Blood Pressure Monitors
11/2011
1Surgical Amputation (Amputations)
04/2010
1Analgesia
05/2006